Chicken Alfredo Lasagna

Featured in: Everyday Suppers

This rich and comforting lasagna combines tender shredded chicken, velvety Alfredo sauce, and fresh spinach in a satisfying layered pasta dish. With a preparation time of 30 minutes and cooking time of 55 minutes, you'll have a restaurant-quality meal ready in under 1.5 hours.

The dish features a creamy ricotta-spinach filling mixed with aromatic garlic and onion, finished with three types of cheese for ultimate indulgence. Perfect for feeding 8 guests or creating impressive leftovers.

Updated on Sun, 18 Jan 2026 13:23:00 GMT
A finished Chicken Alfredo Lasagna with golden melted mozzarella, layered with tender chicken and creamy white sauce in a baking dish. Save Pin
A finished Chicken Alfredo Lasagna with golden melted mozzarella, layered with tender chicken and creamy white sauce in a baking dish. | vectoroven.com

The bubbling sound pulled me into the kitchen before I even opened my eyes that Saturday morning. My sister was bent over the oven, peeking through the glass at what would become our new family staple. She'd been experimenting all week, trying to merge our love for creamy Alfredo with the structure of a proper lasagna. When she finally sliced into that first pan, the layers held perfectly, and the aroma of garlic and melted cheese filled every corner of the house.

I made this for a dinner party once, and my friend who claims she doesnt like spinach scraped her plate clean without realizing shed eaten two cups of greens. The ricotta mixture hides the vegetables so well that even picky eaters dont notice. That night, we sat around the table long after the plates were empty, talking and laughing while the pan sat between us with only a few corner pieces left.

Ingredients

  • Cooked chicken breast: Rotisserie chicken works beautifully here and saves you half an hour of prep time, plus the seasoning adds an extra layer of flavor.
  • Lasagna noodles: Oven ready noodles are tempting, but traditional ones give you more control over texture and they wont soak up too much sauce.
  • Baby spinach: It wilts down to almost nothing, so dont be alarmed by how much raw spinach you start with in the pan.
  • Onion and garlic: These form the aromatic base that keeps the dish from tasting flat or one note.
  • Alfredo sauce: Homemade is divine, but a good jarred sauce works perfectly when youre short on time.
  • Ricotta cheese: Whole milk ricotta creates the creamiest layer, low fat versions can turn grainy when baked.
  • Mozzarella and Parmesan: Freshly shredded melts smoother than pre shredded, which often contains anti caking agents.
  • Egg: This binds the ricotta mixture so it doesnt slide apart when you cut into the lasagna.
  • Italian herbs: Dried herbs bloom beautifully in the ricotta, but you can use fresh if you double the amount.
  • Fresh parsley: A handful of bright green at the end makes the whole dish look like it came from a trattoria.

Instructions

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Prep your oven and dish:
Set the oven to 375°F and grease your baking dish lightly with butter or oil. This keeps the bottom layer from sticking and makes cleanup easier.
Cook the noodles:
Boil them until theyre just bendable, not fully soft, because theyll finish cooking in the oven. Lay them flat on a towel so they dont glue themselves together.
Sauté the aromatics:
Let the onion turn translucent and sweet before you add the garlic, which only needs a minute or itll burn. The kitchen will smell incredible at this point.
Wilt the spinach:
Toss it into the hot pan and watch it shrink down in seconds. Let it cool before mixing with the ricotta or the egg will scramble.
Mix the ricotta filling:
Combine ricotta, egg, half the Parmesan, herbs, salt, pepper, and the cooled spinach until smooth. This layer is what makes the lasagna feel luxurious.
Start layering:
Spread a thin coat of Alfredo on the bottom of the dish to prevent sticking. Lay down your first noodles without overlapping them too much.
Build the first layer:
Spread half the ricotta mixture, scatter half the chicken evenly, drizzle a cup of Alfredo, then sprinkle mozzarella. Press down gently so everything settles.
Repeat the second layer:
Noodles, remaining ricotta spinach blend, rest of the chicken, more Alfredo, more mozzarella. The layers should feel generous but not so tall they topple.
Finish the top:
Final noodles, remaining Alfredo poured evenly, rest of the mozzarella, and a blanket of Parmesan. This top layer will turn golden and bubbly.
Bake covered:
Tent foil over the dish without letting it touch the cheese. Bake for 30 minutes so the inside heats through without the top burning.
Bake uncovered:
Remove the foil and let it go another 20 to 25 minutes until the cheese is browned in spots and the edges are bubbling. The smell will drive you wild.
Rest before serving:
Let it sit for at least 10 minutes so the layers firm up. If you cut too soon, it will slide into a puddle on the plate.
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Quickly chop vegetables, blend sauces, and prepare dips or dressings for fast, everyday meal prep.
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Steaming slice of Chicken Alfredo Lasagna showing pasta sheets, ricotta spinach filling, and bubbling cheese served on a white plate. Save Pin
Steaming slice of Chicken Alfredo Lasagna showing pasta sheets, ricotta spinach filling, and bubbling cheese served on a white plate. | vectoroven.com

One winter evening, I brought this to a potluck where everyone else had made salads and appetizers. It sat in the center of the table like a warm, cheesy monument, and people kept coming back for seconds. A quiet neighbor I barely knew told me it reminded her of Sunday dinners at her grandmothers house, and we ended up talking for an hour. Food has a way of opening doors you didnt know were closed.

How to Store and Reheat

Once the lasagna has cooled completely, cover it tightly with foil or transfer individual portions to airtight containers. It keeps in the fridge for up to four days, and the flavors deepen as it sits. To reheat, cover with foil and warm in a 350°F oven for about 20 minutes, or microwave single servings for two minutes. I actually prefer it the next day when the sauce has soaked into the noodles just a bit more.

Variations You Can Try

Swap the chicken for cooked shrimp or even flaked salmon if you want a seafood twist. You can also add sautéed mushrooms or sun dried tomatoes between the layers for extra depth. If youre feeding vegetarians, leave out the chicken entirely and double the spinach or add roasted zucchini. A pinch of nutmeg in the ricotta mixture brings a subtle warmth that feels very traditional Italian.

What to Serve Alongside

A crisp romaine salad with lemon vinaigrette cuts through the richness perfectly. Garlic bread is always a crowd pleaser, but I like to serve a lighter option like roasted asparagus or green beans with a squeeze of lemon. A chilled glass of Pinot Grigio or sparkling water with a twist of lime keeps things refreshing.

  • Keep a basket of warm bread nearby for soaking up any extra Alfredo that pools on the plate.
  • A simple arugula salad with shaved Parmesan and balsamic adds a peppery contrast.
  • If youre serving kids, a side of steamed broccoli often disappears faster than you expect.
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Freshly baked Chicken Alfredo Lasagna garnished with parsley, perfect with a side salad and glass of Pinot Grigio for dinner. Save Pin
Freshly baked Chicken Alfredo Lasagna garnished with parsley, perfect with a side salad and glass of Pinot Grigio for dinner. | vectoroven.com

This lasagna has earned its spot in my regular rotation, not just because it tastes incredible, but because it turns an ordinary weeknight into something worth gathering around. I hope it becomes one of those recipes you reach for when you want to feed the people you love something that feels like a warm hug on a plate.

Recipe FAQs

Can I use fresh pasta sheets instead of dried noodles?

Yes, fresh pasta sheets work wonderfully and can reduce cooking time. Layer them directly without pre-cooking if using no-boil varieties. Traditional fresh sheets may need brief cooking depending on thickness.

How do I make homemade Alfredo sauce?

Melt butter over medium heat, whisk in flour to create a roux, gradually add warm milk while stirring constantly, then fold in Parmesan cheese and season with salt, pepper, and nutmeg. This takes about 10 minutes and yields creamier results than store-bought versions.

Can I prepare this ahead of time?

Absolutely. Assemble the lasagna completely, cover tightly with plastic wrap and refrigerate up to 24 hours before baking. Add 10-15 minutes to the cooking time when baking from cold. You can also freeze unbaked lasagna for up to 3 months.

What's the best way to slice lasagna cleanly?

Allow the dish to rest for 10-15 minutes after baking as specified in instructions. Use a sharp knife dipped in hot water, wiping between cuts. This resting period lets the cheese set slightly, preventing messy layers.

How can I make this vegetarian?

Omit the chicken and increase the spinach to 3-4 cups. Consider adding sautéed mushrooms, zucchini, or sun-dried tomatoes for heartiness. You might also incorporate roasted eggplant or artichoke hearts for Mediterranean flavors.

What wine pairs best with this dish?

Pinot Grigio is ideal as suggested, offering crisp acidity to cut through richness. Alternatively, try Vermentino, Gavi, or a light Chardonnay. For red wine lovers, a lighter Pinot Noir complements the creamy sauce beautifully.

Chicken Alfredo Lasagna

Layers of tender chicken, creamy Alfredo sauce, spinach, and mozzarella between pasta sheets for a comforting Italian-American meal.

Time to prepare
30 minutes
Time to cook
55 minutes
Overall Time
85 minutes
Created by Lucas Jenkins


Level Medium

Cuisine Italian-American

Makes 8 Portions

Special Diets None specified

What You Need

Proteins

01 3 cups cooked chicken breast, shredded or diced

Pasta

01 12 lasagna noodles, regular or oven-ready

Vegetables

01 2 cups fresh baby spinach, roughly chopped
02 1 medium onion, finely diced
03 3 cloves garlic, minced

Sauces & Dairy

01 4 cups Alfredo sauce, store-bought or homemade
02 2 cups whole milk ricotta cheese
03 2 cups shredded mozzarella cheese
04 1 cup grated Parmesan cheese
05 1 large egg

Spices & Seasonings

01 1 teaspoon dried Italian herbs (basil, oregano, thyme)
02 1/2 teaspoon salt
03 1/4 teaspoon black pepper
04 2 tablespoons fresh parsley, chopped for garnish

How-To Steps

Step 01

Prepare baking dish and noodles: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish. Cook lasagna noodles according to package directions until al dente, then drain and set aside.

Step 02

Sauté aromatics and wilt spinach: Heat a skillet over medium heat with a splash of olive oil. Sauté diced onion for 3-4 minutes until softened. Add minced garlic and cook 1 minute more. Stir in chopped spinach and cook until wilted, approximately 2 minutes. Remove from heat and cool slightly.

Step 03

Prepare ricotta-spinach mixture: In a medium bowl, combine ricotta cheese, egg, half the Parmesan cheese, Italian herbs, salt, and pepper. Mix in the cooled spinach mixture until evenly incorporated.

Step 04

Assemble first layer: Spread 1/2 cup Alfredo sauce on the bottom of the prepared baking dish. Arrange 4 noodles over sauce. Spread half the ricotta-spinach mixture over noodles. Scatter half the chicken on top. Drizzle with 1 cup Alfredo sauce and sprinkle with 2/3 cup mozzarella.

Step 05

Build second layer: Layer 4 noodles over the cheese. Spread remaining ricotta-spinach mixture over noodles. Scatter remaining chicken on top. Drizzle with 1 cup Alfredo sauce and sprinkle with 2/3 cup mozzarella.

Step 06

Top final layer: Arrange final 4 noodles on top. Pour remaining Alfredo sauce over noodles. Sprinkle with remaining mozzarella and Parmesan cheese.

Step 07

Bake covered then uncovered: Cover baking dish with foil and bake for 30 minutes. Remove foil and continue baking for 20-25 minutes until the top is bubbly and golden brown.

Step 08

Rest and serve: Remove from oven and let stand for 10-15 minutes before slicing. Garnish with fresh parsley if desired.

What You’ll Need

  • 9x13-inch baking dish
  • Large skillet
  • Medium mixing bowl
  • Saucepan for homemade Alfredo sauce preparation
  • Measuring cups and spoons
  • Aluminum foil

Allergy Details

Review every component for allergens. See a health expert if unsure.
  • Contains wheat from pasta
  • Contains milk and milk products
  • Contains eggs
  • May contain tree nuts if using nut-based Alfredo sauce

Nutrition details (each serving)

Only for informational use—this isn't a substitute for a doctor's advice.
  • Energy: 510
  • Fat Content: 27 grams
  • Carbohydrates: 33 grams
  • Proteins: 34 grams